抗-内皮素受体A 兔抗

MFCD01092540

NA.41

The epitope is highly conserved in human, swine, bovine and chicken ET-A.

synthetic peptide corresponding to amino acids 413-426 of rat ET-A (with additional N-terminal cysteine).

Anti-Endothelin Receptor A antibody produced in rabbit is suitable for immunohistochemistry at a dilution of 1:100 using rat brain sections or rat lung paraffin embedded sections and western blotting at a dilution of 1:200 using rat brain membranes and ECL.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

Endothelin receptor type A (ETA, ETAR) is a human G protein-coupled receptor that mediates vasoconstriction of blood vessels. It is involved in tumor cell invasion, survival and metastasis. ETAR mediates the promotion of ET-1 on colon cancer cell survival, invasion and MMP-2 expression by a PI3K-mediated mechanism. It plays a critical role in colon cancer metastasis.

Lyophilized from a solution of phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.05% sodium azide.

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

lyophilized powder

human, pig, bovine, chicken

immunohistochemistry: 1:100 using rat brain sections or rat lung paraffin embedded sections
western blot: 1:200 using rat brain membranes and ECL

P25101

dry ice

−20℃

human ... EDNRA(1909)
rat ... Ednra(24326)

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

H412

P273

Aquatic Chronic 3

13 - Non Combustible Solids

WGK 3