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Factor Va human
基本信息
| MDL number | MFCD01093755 |
| NACRES | NA.61 |
| General description【一般描述】 | Factor Va is the activated form of factor V and the cofactor of Xa. It is a component of the prothrombinase complex. Factor V, a glycoprotein is usually seen in the alpha granules of platelets and in plasma. |
| Biochem/physiol Actions【生化/生理作用】 | Factor V is a key component in blood coagulation systems, where deficiencies can inhibit thrombin generation and affect hemostasis. It has been used in studies of coagulopathic bleeding which occurs following injury and is a leading cause of hospital deaths. Factor Va serves as a receptor and positive effector of factor Xa. Hence it can efficiently help in the conversion of prothrombin to thrombin. |
| Linkage【联系】 | View this factors role in the Coagulation Cascade |
| Unit Definition【单位定义】 | One unit is equivalent to the Factor V activity in 1.0 mL of normal human plasma at pH 7.4 at 37 ℃. |
| Physical form【外形】 | Aqueous solution containing 50% (v/v) glycerol and 5mM CaCl2 |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | human |
| form【形式】 | solution |
| Specific Activity | ≥1500 units/mg protein |
| mol wt【分子量】 | 168 kDa |
| technique(s) | ligand binding assay: suitable |
| UniProt accession no.【UniProt登记号】 | P12259 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... F5(2153) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
