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Monoclonal Anti-Interleukin-4-Carboxyfluorescein antibody produced in mouse
| 产品编号： | 4092537 |
| 规格： | clone 3007.11, purified immunoglobulin, buffered aqueous solution |
| 包装规格： | 100 TEST |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Monoclonal Anti-Interleukin-4-Carboxyfluorescein antibody produced in mouse
Monoclonal Anti-Interleukin-4
Anti-IL-4
基本信息
| NACRES | NA.41 |
| Specificity【特异性】 | The conjugates will identify and quantitate cells containing intracellular forms of human IL-4. |
| Immunogen【免疫原】 | recombinant human IL-4 |
| Biochem/physiol Actions【生化/生理作用】 | Interleukin-4 (IL-4) is a T cell derived chemokine that stimulates the Th2 mediated immune response and proliferation of B cells. The signaling stimulated by IL-4 by binding to its receptors leads to activation of JAK/STAT6 and IRS-mediated PI3K/Akt pathway. IL-4 mediates endocytic activity of macrophages, chemotaxis of leukocytes in response to inflammation, angiogenesis and regulation of nitric oxide metabolism in macrophages. The coupling of Carboxyfluorescein to Anti-Interleukin-4 antibody allows for flow cytometry applications. |
| Physical form【外形】 | Solution in saline containing up to 0.5% bovine serum albumin and up to 0.1% of sodium azide as a preservative. |
| Preparation Note【制备说明】 | Purified antibody is conjugated to carboxyfluorescein (FITC). |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | carboxyfluorescein conjugate |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 3007.11, monoclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | human |
| storage condition【储存条件】 | protect from light |
| technique(s) | flow cytometry: suitable |
| isotype【同位素/亚型】 | IgG1 |
| UniProt accession no.【UniProt登记号】 | P05112 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | 2-8℃ |
| Gene Information | human ... IL4(3565) |
| packaging【包装】 | 100 test in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |
