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氯化乙酰胆碱

Acetylcholine Chloride
产品编号:4092899
规格:≥99% (TLC), free-flowing, Redi-DriTM
CAS NO:60-31-1
包装规格:100 G
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
4092899100 G3230
产品别名

60-31-1

氯化乙酰胆碱

Acetylcholine Chloride

ACh

结构式
基本信息
Linear Formula【线性分子式】
(CH3)3N+CH2CH2OCOCH3Cl-
Molecular weight
181.66
Beilstein
3571875
MDL number
MFCD00011698
Quality【质量】
free-flowing
General description【一般描述】
Acetylcholine is a neurotransmitter released at nerve endings in both the central and peripheral nervous systems. Acetylcholine chloride (C7H16ClNO2) is a stable cholinergic agonist with muscarinic and nicotinic actions. It is available as white or off-white hygroscopic crystals, or as a crystalline powder. Acetylcholine chloride is hygroscopic in nature and is highly soluble in water, alcohol, propylene glycol and chloroform.
Application【应用】
Acetylcholine chloride has been used:
  • as an agent to trigger sudomotor axon reflex response during autonomic test
  • to induce contraction amplitude of pyloric circular smooth muscle strip (PCSMS) in rats
  • as a substrate for acetylcholinesterase
  • to stimulate after discharge in Aplysia bag cell neurons

Biochem/physiol Actions【生化/生理作用】
氯化乙酰胆碱,20mg/kg体重注射,减少小鼠实验性诱发脓毒病的死亡和血浆促炎细胞因子。类胆碱能抗-炎症机制可能通过乙酰胆碱和 α7n单核细胞,巨噬细胞和中性粒细胞上的胆红素受体互作接待,降低了促炎细胞活素,比如 TNF-α,IL-1β,和IL-6。
Caution【注意】
非常吸湿
Legal Information【法律信息】
Redi-Dri is a trademark of sigma-aldrich Co. LLC
产品性质
product line【产品线】
Redi-Dri
Quality Level【质量水平】
100
Assay【测定】
≥99% (TLC)
mp
146-150 ℃ (lit.)
solubility【溶解性】
H2O: 100 mg/mL
SMILES string
[Cl-].CC(=O)OCC[N+](C)(C)C
InChI
1S/C7H16NO2.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1
InChI key
JUGOREOARAHOCO-UHFFFAOYSA-M
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 2
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