1-Pyrrolidinecarbodithioic Acid, Ammonium Salt-CAS 5108-96-3-Calbiochem

C₅H₁₂N₂S₂

164.29

MFCD00012720

Cell permeable. Inhibits the induction of nitric oxide synthase activity in rat alveolar macrophages. Prevents apoptosis in human HL-60 cells and thymocytes, but induces apoptosis in human and rat smooth muscle cells. Inhibits NF-κB activation and HIV replication in lymphocytes.

Cell permeable: yes
Product does not compete with ATP.
Reversible: no
Primary Target
Induction of nitric oxide synthase activity in rat alveolar macrophages

Toxicity: Irritant (B)

Following reconstitution, aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 3 months at -20°C.







From Catalog:

Desc. Field- added "cell-permeable"

Tsai, J.C., et al. 1996. J. Biol. Chem.271, 3667.
Pan, Z., et al. 1995. J. Biol. Chem.270, 7787.
Bessho, R., et al. 1994. Biochem. Pharmacol.48, 1883.
Sherman, M.P., et al. 1993. Biochem. Biophys. Res. Commun.191, 1301.
Schreck, R., et al. 1992. J. Exp. Med.175, 1181.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

100

≥98% (titration)

solid

Calbiochem^®

OK to freeze
desiccated (hygroscopic)

white

water: 1 mg/mL

ambient

2-8℃

1S/C5H9NS2.H3N/c7-5(8)6-3-1-2-4-6;/h1-4H2,(H,7,8);1H3

MDDIUTVUBYEEEM-UHFFFAOYSA-N

100 mg in Plastic ampoule

11 - Combustible Solids

WGK 3