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HBcAg 核心 人
HBcAg core human
| 产品编号： | 4093811 |
| 规格： | ~1 mg/mL, ≥95% (SDS-PAGE), recombinant, expressed in E. coli |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
HBcAg 核心 人
HBcAg core human
Hepatitis B virus core antigen
基本信息
| MDL number | MFCD02264925 |
| NACRES | NA.32 |
| General description【一般描述】 | amino acids 1-183 of HBV core antigen. |
| Biochem/physiol Actions【生化/生理作用】 | HBcAg core human is a capsid protein of hepatitis B virus (HBV). It acts as a viral factor for HBV clearance. HBcAg is implicated in viral replication. Hepatitis B virus core antigen (HBcAg) is a positive control for human HBV antibodies.In humans with chronic HBV (hepatitis B virus) infection, cytotoxic effects of blood T lymphocytes can be suppressed by incubating cells with antibodies against hepatitis B core antigen (HBcAg). The antigen can also work as a T-cell independent antigen in athymic mice. However, it is an efficient immunogen, resulting in T-cell activation and increased anti-HBc levels. High cytoplasmic/membranous expression of HBcAg is associated with increased liver inflammation. |
| Physical form【外形】 | Solution in 50% glycerol, 7.5 mM phosphate buffer, pH 7.2, 75 mM NaCl. |
产品性质
| Quality Level【质量水平】 | 200 |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥95% (SDS-PAGE) |
| mol wt【分子量】 | 18 kDa |
| concentration【浓度】 | ~1 mg/mL |
| UniProt accession no.【UniProt登记号】 | G9G988 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | hepatitis B virus ... HBVgp4(944568) human ... HBVgp4(944568) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
