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Isocitrate Dehydrogenase 1 (NADP+) human
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4094041 | 10 μG | 8280 |
产品别名
9028-48-2
Isocitrate Dehydrogenase 1 (NADP+) human
idh1
Isocitrate Dehydrogenase Cytoplasmic
基本信息
| Enzyme Commission (EC) Number【酶学委员会(EC)编号】 | 1.1.1.42 ( BRENDA | IUBMB ) |
| NACRES | NA.54 |
| General description【一般描述】 | Human Isocitrate Dehydrogenase (IDH1), also known as oxalosuccinate decarboxylase, full length [amino acids 1-414 (end)] with C-terminal FLAG-tag, expressed in Sf9 cells via a baculovirus expression system. |
| Application【应用】 | Human Isocitrate Dehydrogenase (IDH1) is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. It may be useful as a biomarker for diagnosis and prognosis prediction of non-small cell lung cancer . |
| Biochem/physiol Actions【生化/生理作用】 | Human Isocitrate Dehydrogenase (IDH1), also known as oxalosuccinate decarboxylase, is a full length amino acid with a C-terminal FLAG-tag and is expressed in Sf9 cells via a baculovirus expression system. IDH1 expression has been correlated with poor survival of non-small cell lung cancer. IDH1 promotes tumor growth . |
| Physical form【外形】 | Solution in 45 mM Tris-HCl, 124 mM NaCl, 2.4 mM KCl, 90 μg/ml FLAG peptide, 3 mM DTT, and 10% glycerol at pH 8.0. |
产品性质
| Quality Level【质量水平】 | 200 |
| recombinant【重组】 | expressed in Sf9 cells |
| Assay【测定】 | ≥0.30 mg/mL protein basis (Bradford) ≥90% (SDS-PAGE) |
| form【形式】 | buffered aqueous glycerol solution |
| mol wt【分子量】 | 47.6 kDa |
| NCBI accession no.【NCBI登记号】 | NM_005896 |
| relevant disease(s)【相关疾病】 | cancer (lung) |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
