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Interleukin-17 from mouse
| 产品编号： | 4094048 |
| 规格： | ≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture |
| 包装规格： | 25 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Interleukin-17 from mouse
IL-17
CTLA-8
基本信息
| MDL number | MFCD01635117 |
| NACRES | NA.32 |
| Biochem/physiol Actions【生化/生理作用】 | Interleukin 17 (IL-17), initially known as CTLA-8, is a T cell-expressed polypeptide that appears to be involved in the regulation of the hematopoietic system. IL-17 has been shown to induce IL-6, IL-8, and G-CSF production by fibroblasts; all of these cytokines have demonstrated effects on hematopoiesis. IL-17 (interleukin-17) participates in the activation of nuclear factor-κB and mitogen-activated protein kinase pathways and CCAAT/enhancer-binding protein family of transcription factors, thereby regulating pro-inflammatory and antimicrobial genes. In rheumatoid arthritis, IL-17 is responsible for the inflammation as well as destruction of joints. |
| Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% trifluoroacetic acid containing 1.25 mg of bovine serum albumin. |
| Analysis Note【分析说明】 | The biological activity of mouse IL-17 is measured by its ability to induce IL-6 production using NIH/3T3 cells. |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | mouse |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥97% (SDS-PAGE) |
| form【形式】 | lyophilized powder |
| mol wt【分子量】 | 16.5 kDa |
| packaging【包装】 | pkg of 25 μg |
| technique(s) | cell culture | mammalian: suitable |
| impurities【杂质】 | endotoxin, tested |
| UniProt accession no.【UniProt登记号】 | Q62386 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | mouse ... Il17a(16171) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
