GMBS

C₁₂H₁₂N₂O₆

280.23

MFCD00036817

Heterobifunctional reagent useful for preparation of conjugates such as secondary antibodies and β-galactosidase for EIA procedures or for immobilizing enzymes on solid supports.
N-γ-maleimidobutyryloxysuccinimide ester (GMBS) is an aliphatic crosslinker for immunotoxins (IT).(1) It is used for the generation of conjugated Poly-γ-D-glutamic acid.

GMBS is suitable for use:

• as a hetero-bifunctional cross-linking reagent for the immobilization of neural adhesion molecule L1 onto silicon dioxide surface
• for the crosslinking of biochips with functionalized gold nanoparticles
• for coating salinized capillary tube prior to neutravidin treatment in biosensor sandwich immunoassay

Toxicity: Irritant (B)

Reconstitute to 10 mg/ml in tetrahydrofuran or DMSO. Add 1 ml of this stock solution dropwise, with stirring, to 10 ml of 20 mM phosphate buffer.

Rusin, K.M., et al. 1992. Biosens. Bioelectron. 7, 367.
Kitagawa, T., et al. 1983. J. Biochem. 94, 1160.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

≥90% (HPLC)

100

solid

Calbiochem^®

OK to freeze

−20℃

1S/C12H12N2O6/c15-8-3-4-9(16)13(8)7-1-2-12(19)20-14-10(17)5-6-11(14)18/h3-4H,1-2,5-7H2

PVGATNRYUYNBHO-UHFFFAOYSA-N

11 - Combustible Solids

WGK 3