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18:1-2:0 DG
| 产品编号： | 4095267 |
| 规格： | 1-oleoyl-2-acetyl-sn-glycerol, neat oil |
| CAS NO： | 86390-77-4 |
| 包装规格： | 10 MG，25 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Avanti |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4095267 | 10 MG | 1230 | |||
| 4095267 | 25 MG | 2190 |
产品别名
86390-77-4
18:1-2:0 DG
1--(9Z-octadecenoyl)-2-acetoyl-sn-glycerol; DG(18:1(9Z)/2:0/0:0); OAG
基本信息
| Empirical Formula【经验(实验)分子式】 | C23H42O5 |
| Molecular weight | 398.58 |
| General description【一般描述】 | 18:1-2:0 DG, also called 1-oleoyl-2-acetyl-sn-glycerol (OADG), is a membrane permeable and synthetic analog of diacyl glycerol (DAG). |
| Application【应用】 | 18:1-2:0 DG (1-oleoyl-2-acetyl-sn-glycerol) may be used:
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| Biochem/physiol Actions【生化/生理作用】 | 18:1-2:0 DG (OAG) halts the inhibition of glucose uptake by the phospholipase C (PLC) inhibitor, U73122. It also inhibits mitochondrial permeability transition pore (MPTP) formation and prevents fatty acid release and necrosis in lung fibroblasts. OAG is a protein kinase C (PKC) activator. It also inhibits TWIK-related acid-sensitive (TASK)-like potassium channels in peripheral arterial chemoreceptors. OAG stimulates 5-lipooxygenase (5-LO) in human polymorphonuclear leukocytes (PMNL). |
| Other Notes【其他说明】 | Effective concentration: Most biological responses saturate at 20 to 250 μM sn-1,2-dioctanoylglycerol. Only sn-1,2 isomers appear to be active. Precaution: Since short chain Diacylglycerols mimic effects of the tumor-promoting phorbol diesters in a number of biological systems, extra care should be employed in their handling. Treatment of solutions, vessels and other articles with 1N NaOH before washing or discarding will destroy diacylglycerols. Delivery to cells: Dry samples of diacylglycerol in chloroform, using a stream of nitrogen. Dissolve the residue in an appropriate volume of ethanol or DMSO, then dilute to the desired aqueous medium. |
产品性质
| Assay【测定】 | >99% (TLC) |
| manufacturer/tradename | Avanti Polar Lipids 800100O |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| InChI | 1S/C23H42O5/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(26)27-20-22(19-24)28-21(2)25/h10-11,22,24H,3-9,12-20H2,1-2H3/b11-10-/t22-/m0/s1 |
| InChI key | PWTCCMJTPHCGMS-YRBAHSOBSA-N |
| packaging【包装】 | 5 mL PTFE Vial with Screw Cap (800100O-25mg) 5 mL PTFE Vial with Screw Cap (800100O-10mg) |
产品说明
| Storage and Stability【储存及稳定性】 | Diacylglycerols are conveniently stored in chloroform solutions in glass vials with PTFE-lined caps at -20℃. Under these conditions acyl migration is minimal. Avoid plastic when handling chloroform solutions. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
