Sphinganine (d18:0)

C₁₈H₃₉NO₂

301.51

NA.25

Sphinganine (d18:0) is a substrate for the enzyme ceramide desaturase. It is synthesized indirectly due to the interconversion of supplemented glycine to serine. Sphinganine (d18:0) is catabolized to ceramide.

Sphinganine (d18:0) has been used:

• as a standard in liquid chromatography tandem mass spectrophotometry for the quantification of epidermal ceramides
• as a medium supplement to test its effect on growth of yeast cells
• in the preparation of bovine serum albumin lipid complex to investigate its effect on non-lysosomal - glucosylceramidase β2 (GBA2) inhibition

Sphinganine (d18:0) levels are not altered in hereditary sensory neuropathy type 1 cells. Accumulation of d18:0 is observed in tumor hypoxia. It is useful as a biomarker for studying microbial diversity.

powder

Avanti Polar Lipids 860498P

dry ice

−20℃

OC[C@@](N)([H])[C@]([H])(O)CCCCCCCCCCCCCCC

1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3/t17-,18+/m0/s1

OTKJDMGTUTTYMP-ZWKOTPCHSA-N

5 mL Amber Glass Screw Cap Vial (860498P-25mg)
5 mL Amber Glass Screw Cap Vial (860498P-100mg)
5 mL Amber Glass Screw Cap Vial (860498P-10mg)

13 - Non Combustible Solids

WGK 3