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14:0 心磷脂(铵盐)
14:0 Cardiolipin (ammonium salt)
| 产品编号： | 4095386 |
| 规格： | 1′,3′-bis[1,2-dimyristoyl-sn-glycero-3-phospho]-glycerol (ammonium salt), powder |
| CAS NO： | 63988-20-5 |
| 包装规格： | 25 MG，200 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Avanti |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4095386 | 25 MG | 1380 | |||
| 4095386 | 200 MG | 4340 |
产品别名
63988-20-5
14:0 心磷脂(铵盐)
14:0 Cardiolipin (ammonium salt)
1,1′,2,2′-tetramyristoyl cardiolipin (ammonium salt); 1,1′,2,2′-tetratetradecanoyl cardiolipin (ammonium salt); CL(1′-[14:0/14:0],3′-[14:0/14:0])
基本信息
| Empirical Formula【经验(实验)分子式】 | C65H132N2O17P2 |
| Molecular weight | 1275.69 |
| NACRES | NA.25 |
| General description【一般描述】 | 14:0 Cardiolipin or TMCL (1,1′,2,2′-tetramyristoyl cardiolipin) is a saturated CL and exists as gel at low temperatures. Cardiolipin is an anionic phospholipid. The 14:0 indicates the fatty acyl substituents attached to the carbons of glycerol. It is localized to the inner mitochondrial membrane. |
| Application【应用】 | 14:0 Cardiolipin (ammonium salt) has been used as stable isotope-labeled standard prior to yeast strains high performance liquid chromatography electrospray ionization-tandem mass spectrometry (HPLC-ESI-MS/MS). It may be used as an internal standard in mass spectroscopy and in liposome preparation for electrophysiological studies. 14:0 Cardiolipin (ammonium salt) may be used in lipopeptide synthesis. |
| Biochem/physiol Actions【生化/生理作用】 | TMCL (1,1′,2,2′-tetramyristoyl cardiolipin) bilayers are useful in generating multilamellar vesicles. Defects in the cardiolipin metabolic associated with Barth syndrome patients. Liposomes of TMCL with 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and cholesterol are potential drug-delivery systems. TMCL displays temperature dependent thermotropic phase transitions. Cardiolipin participates in proton uptake pathway and also maintains the structure of enzymes involved. Cardiolipin maintains the mitochondrial function, membrane potential and structural support for the inner mitochondrial membrane and proteins in it. Concentration and composition changes of cardiolipin have been implicated in pathological conditions including ischemia, hypothyroidism, aging, heart failure and cardioskeletal myopathy.) Cardiolipin can form micelles/vesicles naturally. |
产品性质
| Assay【测定】 | >99% (TLC) |
| form【形式】 | powder |
| manufacturer/tradename | Avanti Polar Lipids 710332P |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (710332P-25mg) 5 mL Amber Glass Screw Cap Vial (710332P-200mg) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
