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08:0 PA

产品编号:4095455
规格:1,2-dioctanoyl-sn-glycero-3-phosphate (sodium salt), powder
CAS NO:321883-54-9
包装规格:10 MG
产品类别:进口试剂
品牌:Avanti
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
409545510 MG2680
产品别名

321883-54-9

08:0 PA

PA(8:0/8:0)

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C19H36O8PNa
Molecular weight
446.45
NACRES
NA.25
General description【一般描述】
Phosphatidic acid is obtained from glycerophospholipid with the help of phospholipase D. 08:0 PA/1,2-dioctanoyl-sn-glycero-3-phosphate (C8-PA) is an mammalian target of rapamycin (mTOR) activator.
Application【应用】
08:0 PA may be used to activate p-mTOR in order to assess whether the observed apoptotic effect of histone deacetylase inhibitors (HDACIs) is related to mammalian target of rapamycin (mTOR) pathway signaling.
Biochem/physiol Actions【生化/生理作用】
Phosphatidic acid might serve as a modulator of phagocyte respiratory burst. It also acts as a precursor of diacylglycerol and lysophosphatidic acid. 08:0 PA/C8-PA has the ability to affect the phosphorylation of mammalian target of rapamycin (mTOR) and the viability of gallbladder carcinoma cells, that are treated with histone deacetylase inhibitors (HDACIs).
产品性质
Assay【测定】
>99% (TLC)
form【形式】
powder
manufacturer/tradename
Avanti Polar Lipids 830842P
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
SMILES string
[H][C@@](COP([O-])(O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[Na+]
packaging【包装】
5 mL Clear Glass Sealed Ampule (830842P-10mg)
5 mL Clear Glass Sealed Ampule (830842P-25mg)
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
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