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18:0-20:4 PI(3,4)P2
产品别名
18:0-20:4 PI(3,4)P2
1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′-bisphosphate) (ammonium salt)
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C47H94N3O19P3 |
| Molecular weight | 1098.18 |
| General description【一般描述】 | PI(3,4)P2 is a lipid secondary messenger. It is obtained from the dephosphorylation of PI(3,4,5)P3 by 5-phosphatase. |
| Biochem/physiol Actions【生化/生理作用】 | PI(3,4)P2 plays a role in protein kinase B (PKB) phosphorylation on Ser473 in mast cells. It also binds to certain effectors such as serine/threonine-specific protein kinase (AKT) and dual adaptor of phosphotyrosine and 3-phosphoinositides 1 (DAPP1). It also regulates the activity of actin mesh which is associated with endocytic structures. |
产品性质
| form【形式】 | powder |
| manufacturer/tradename | Avanti Polar Lipids |
| technique(s) | thin layer chromatography (TLC): 99% |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](OP([O-])(O)=O)[C@@H](OP(O)([O-])=O)[C@H]1O)=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+].[NH4+] |
| packaging【包装】 | 2 mL Amber Serum Vial with Stopper and Crimp Cap (850188P-100UG) 2 mL Amber Serum Vial with Stopper and Crimp Cap (850188P-500UG) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
