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Milli-Mark® Anti-CD11B-PE Antibody, clone 2LPM19c
| 产品编号： | 4096008 |
| 规格： | clone 2LPM19c, Milli-Mark®, from mouse |
| 包装规格： | 100 TESTS |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Milli-Mark® Anti-CD11B-PE Antibody, clone 2LPM19c
Integrin alpha-M, Cell surface glycoprotein MAC-1 subunit alpha, CR-3 alpha chain, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, CD11 antigen-like family member B
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.44 |
| General description【一般描述】 | CD11b is the 165 kDa α-chain of the Mac-1 complex. The molecule, also called CR3, functions as a cell surface receptor for the C3bi complement fragment. There is evidence that CD11b can bind fibrinogen in addition to C3bi (Wright,1988). Two binding sites have now been reported, one recognizing lipopolysaccharide, and the other protein ligands containing the arg-gly-asp sequence (Wright, 1989). Binding of the coagulation factor X has also been suggested as an additional receptor role of CD11b (Altieri,1988). This protein belings to a family of related heterodimeric proteins designated CD11 in the classification system for human leucocyte differentiation antigens, which shares a common β-chain with a MW of 95 kDa (CD18). Besides the C3bi receptor, this protein family contains two other members, leucocyte function associated-1 (LFA-1, C11a) antigen and p150,95 protein (CD11c) (Sanchez-Madrid,1983). |
| Specificity【特异性】 | Antibody recognizes Human CD11b antigen. |
| Immunogen【免疫原】 | Purified iC3b receptor. |
| Application【应用】 | Milli-Mark Anti-CD11B-PE Antibody, clone 2LPM19c detects level of CD11B & has been published & validated for use in FC. Research Sub Category Immunoglobulins & Immunology Research Category Inflammation & Immunology |
| Quality【质量】 | Evaluated by flow cytometry using human PBMCs |
| Physical form【外形】 | Protein A purified Purified Mouse monoclonal IgG1 conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2. |
| Analysis Note【分析说明】 | Control PBMCs |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
| Legal Information【法律信息】 | MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | PE |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 2LPM19c, monoclonal |
| species reactivity | human |
| manufacturer/tradename | Milli-Mark® |
| technique(s) | flow cytometry: suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NP_000623.2 |
| UniProt accession no.【UniProt登记号】 | P11215 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | 165 kDa (Wright, 1988) |
| Storage and Stability【储存及稳定性】 | Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
