Src human

MFCD03458574

NA.32

SRC proto-oncogene, non-receptor tyrosine kinase (SRC) belongs to the family of non-receptor tyrosine kinases. It contains an amino-terminal domain, conserved Src-homology domains (SH2 and SH3), a tyrosine kinase domain and the carboxyl-terminus. The gene encoding this protein is localized on human chromosome 20q11.23.

Human Src has been used to study the kinetics of Src entrapped in a series of different sol-gel derived materials.

SRC proto-oncogene, non-receptor tyrosine kinase (SRC) phosphorylates membrane proteins and nucleoproteins and activates various intracellular signaling cascades. It has been associated with a number of human malignancies and cancers.

One unit will phosphorylate one nmole of poly(Gly:Tyr) 4:1 per minute at pH 7.5 at 30℃.

Solution in 50 mM Tris pH 7.5, 0.05 mM EDTA, 1 mM DTT, 100 mM NaCl, 0.05% NP-40, and 50% glycerol.

200

expressed in baculovirus infected insect cells

≥80% (SDS-PAGE)

buffered aqueous glycerol solution

60 kDa

~0.58 mg/mL protein (Bradford assay)

P12931

cell analysis

dry ice

−70℃

human ... SRC(6714)

12 - Non Combustible Liquids

WGK 1