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Sonic Hedgehog Peptide from mouse
| 产品编号： | 4096463 |
| 规格： | ≥97% (SDS-PAGE), recombinant, expressed in E. coli, Fused to a histidine tag at the C-terminus, lyophilized powder |
| 包装规格： | 25 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Sonic Hedgehog Peptide from mouse
Shh
基本信息
| MDL number | MFCD03792594 |
| NACRES | NA.32 |
| General description【一般描述】 | Sonic hedgehog (Shh) is a morphogenic glycoprotein. The gene encoding it is localized on mouse chromosome 5. |
| Application【应用】 | Sonic hedgehog peptide from mouse has been used for neural differentiation. |
| Biochem/physiol Actions【生化/生理作用】 | Cell signaling peptide involved in embryonic morphogenic development of several tissues including Hensen′s node, the notochord, and the neural tube. Sonic hedgehog (Shh) has a role in fracture healing and regeneration. The protein associates with its receptor Patched (Ptc-1), de-represses Smoothened (Smo) and activates the Gli family of transcription factors. Mutations in the Shh pathway have been linked to developmental diseases and cancer. |
| Other Notes【其他说明】 | N-terminal peptide encoding amino acid residues 25-198. |
| Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline, pH 7.4, containing 5% trehalose and 50 μg of bovine serum albumin per 1 μg of cytokine. |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | mouse |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥97% (SDS-PAGE) |
| form【形式】 | lyophilized powder |
| potency【效能】 | 0.4-3.0 μg/mL ED50 |
| mol wt【分子量】 | predicted mol wt 20 kDa |
| packaging【包装】 | pkg of 25 μg |
| storage condition【储存条件】 | avoid repeated freeze/thaw cycles |
| impurities【杂质】 | <1 EU/μg |
| UniProt accession no.【UniProt登记号】 | Q62226 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | mouse ... Shh(20423) |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
