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α-Synuclein E46K 人
α-Synuclein E46K human
| 产品编号： | 4096468 |
| 规格： | recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder |
| 包装规格： | 500 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
α-Synuclein E46K 人
α-Synuclein E46K human
PD1
PARK1
PARK4
NACP (Non-a-beta component of Alzheimer disease amyloid, precursor)
non A4 component of amyloid precursor
基本信息
| NACRES | NA.32 |
| Biochem/physiol Actions【生化/生理作用】 | Among the familial mutations of α-synuclein in Parkinson′s disease, E46K has the greatest potential to aggregate. This mutation is a 188G-A transition resulting in a Glu46-to-Lys (E46K) substitution in the amino-terminal region of the protein. Deposition of α-synuclein as fibrillary tangles is a hallmark of certain neurodegenerative diseases including Parkinson′s. Among the familial mutations of α-synuclein, E46K has the greatest potential to aggregate. |
产品性质
| Quality Level【质量水平】 | 200 |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥90% (SDS-PAGE) |
| form【形式】 | lyophilized powder |
| mol wt【分子量】 | apparent mol wt 19-20 kDa |
| UniProt accession no.【UniProt登记号】 | P37840 |
| compatibility【相容性】 | for use with ABI StepOnePlus |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... SNCA(6622) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
