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Ubiquitin-Specific Protease 8 human
| 产品编号： | 4099892 |
| 规格： | recombinant, expressed in Sf9 cells, ≥70% (SDS-PAGE) |
| 包装规格： | 50 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品性质
| Quality Level【质量水平】 | 200 |
| recombinant【重组】 | expressed in Sf9 cells |
| Assay【测定】 | ≥0.10 mg/mL protein basis (Bradford) ≥70% (SDS-PAGE) |
| form【形式】 | buffered aqueous glycerol solution |
| mol wt【分子量】 | 128 kDa |
| NCBI accession no.【NCBI登记号】 | NM_005154 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
基本信息
| General description【一般描述】 | Human USP8 (Ubiquitin-Specific Protease 8) or UBPY, amino-acids 2-1118 (end) with an N-terminal FLAG-tag, expressed in a baculovirus-infected Sf9 cell expression system. |
| Application【应用】 | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| Biochem/physiol Actions【生化/生理作用】 | Expression of ubiquitin-specific protease 8 (USP8) in mice is critical for proper expression and stability of several growth factor receptors including epidermal growth factor receptor. However, USP8 was shown to degrade chemokine receptor 4. |
| Physical form【外形】 | Solution in 45 mM Tris-HCl, 124 mM NaCl, 2.4 mM KCl, 90 ng/μl Flag peptide, 3 mM DTT, and 20% Glycerol at pH 8.0. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
