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Peroxynitrite
基本信息
eCl@ss | 32160405 |
NACRES | NA.41 |
General description【一般描述】 | Peroxynitrite (ONOO−) is a powerful oxidant formed by the collision of nitric oxide and superoxide. |
Application【应用】 | Peroxynitrite has been used to induce pericyte contraction in mouse brains. It has also been used for the preparation of positive control nitrated protein standards in immunohistochemical studies. |
Biochem/physiol Actions【生化/生理作用】 | Peroxynitrite (ONOO−) exhibits bactericidal activity. It promotes cell death and contributes to the signal-transduction process, mitochondrial function, and apoptotic pathway. The formation of peroxynitrite has been associated with the development of various diseases including vascular diseases, ischemia-reperfusion injury, circulatory shock, inflammation, pain, and neurodegeneration. |
Quality【质量】 | Routinely evaluated by treating non-stimulated A431 cells. |
Physical form【外形】 | 0.3M NaOH |
Legal Information【法律信息】 | UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
manufacturer/tradename | Upstate® |
technique(s) | western blot: suitable |
shipped in【运输】 | dry ice |
产品说明
【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Pictograms【象形图】 | GHS05 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H290 - H315 - H319 |
Precautionary Statements | P234 - P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 |
Hazard Classifications【危险分类】 | Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 |
Storage Class Code【储存分类代码】 | 8B - Non-combustible, corrosive hazardous materials |
WGK | WGK 2 |