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Imidazole
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4101954 | 100 G | 9040 |
产品别名
288-32-4
咪唑
Imidazole
1,3-Diaza-2,4-cyclopentadiene
Glyoxaline
甘恶啉
1,3-二氮杂-2,4-环戊二烯
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C3H4N2 |
Molecular weight | 68.08 |
Beilstein | 103853 |
MDL number | MFCD00005183 |
Quality【质量】 | free-flowing |
General description【一般描述】 | Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents. |
Application【应用】 | Imidazole has been used
特别适用于 pH 6.2-7.8 范围内的缓冲液 |
Biochem/physiol Actions【生化/生理作用】 | Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC). |
Legal Information【法律信息】 | Redi-Dri is a trademark of sigma-aldrich Co. LLC |
产品性质
Quality Level【质量水平】 | 100 |
grade【等级】 | for molecular biology |
vapor pressure【蒸汽压】 | <1 mmHg ( 20 ℃) |
product line【产品线】 | Redi-Dri™ |
Assay【测定】 | ≥99% (titration) |
form【形式】 | crystalline powder |
pH【pH值(酸碱度)】 | 6.2-7.8 (25 ℃) |
pKa (25 ℃) | 6.95 |
bp | 256 ℃ (lit.) |
mp | 88-91 ℃ (lit.) |
application(s) | diagnostic assay manufacturing |
foreign activity【异质活性】 | DNase, RNase and protease, none detected |
SMILES string | c1c[nH]cn1 |
InChI | 1S/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5) |
InChI key | RAXXELZNTBOGNW-UHFFFAOYSA-N |
安全信息
Pictograms【象形图】 | GHS05,GHS07,GHS08 |
Signal word【警示用语:】 | Danger |
Hazard Statements | H302 - H314 - H360D |
Precautionary Statements | P201 - P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338 + P310 - P308 + P313 |
Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1C |
Storage Class Code【储存分类代码】 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
WGK | WGK 2 |
Flash Point(F)【闪点(F)】 | 293.0 °F - closed cup |
Flash Point(C)【闪点(C)】 | 145 ℃ - closed cup |