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Eotaxin human
| 产品编号： | 4102021 |
| 规格： | recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC) |
| 包装规格： | 20 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Eotaxin human
Eosinophil chemotactic protein chemokine (C-C motif) ligand 11
MGC22554
CCL11
SCYA11
Small inducible cytokine A11
基本信息
| MDL number | MFCD01093487 |
| NACRES | NA.32 |
| General description【一般描述】 | Eotaxin is a chemokine and belongs to the Th2 (T helper 2) cytokine family. It is expressed in many organs, such as heart, central nervous system and the cerebrospinal fluid. The associated gene (CCL11 (C-C motif chemokine ligand 11)) is mapped to human chromosome 17q12. |
| Biochem/physiol Actions【生化/生理作用】 | Eotaxin participates in immunoregulatory and inflammatory responses. It works as a chemoattractant for many immune cells, including eosinophils, basophils, myeloid cells and T-helper 2 lymphocytes. The eotaxin gene is associated with atopic dermatitis, allergic rhinitis, sinusitis, asthma, ulcerative colitis, gastrointestinal disorders and parasitic infections. It is also involved with the pathogenesis of ovarian and gastric cancer. Eotaxin plays a significant role in the aging processes. |
| Physical form【外形】 | Sterile filtered and Lyophilized without additives. |
| Reconstitution【重悬】 | Reconstituted in water to a concentration of 0.1-1 μg/μL. It is recommended that further dilutions be made into buffer containing carrier protein or medium containing serum. Centrifuge the vial prior to opening. Avoid freeze-thaw cycles. |
产品性质
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥97% (HPLC) ≥97% (SDS-PAGE) |
| form【形式】 | lyophilized |
| potency【效能】 | 10 ng/mL |
| mol wt【分子量】 | ~8.3 kDa |
| packaging【包装】 | pkg of 20 μg |
| storage condition【储存条件】 | avoid repeated freeze/thaw cycles |
| impurities【杂质】 | endotoxin, tested |
| NCBI accession no.【NCBI登记号】 | P51671 |
| UniProt accession no.【UniProt登记号】 | P51671 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... CCL11(6356) |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
