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Anti-CD28 Antibody, clone 15E8
产品别名
Anti-CD28 Antibody, clone 15E8
TP44
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
Specificity【特异性】 | This antibody reacts with the 44 kDa antigen found on a sub-population of T cells and activated B cells. These CD28+ CD8 cells are now known to be cytotoxic T cell precursors. The antibody does not react with B cells, granulocytes or monocytes. The ligand for CD28 is CD80 (B7) which is found on activated B cells suggesting a role for CD28 in T and B cell interaction FUSION PARTNER: SP2/0 |
Immunogen【免疫原】 | Human T lymphocytes |
Application【应用】 | To study the role of CD28 in T cell proliferation. The antibody will induce the proliferation of resting T lymphocytes. This antibody will act in cell stimulation studies where it has been suggested that measuring T cell function in HIV infected asymptomatic patients may be an early indicator of AIDS, independent of CD4 + cell counts Optimal working dilutions must be determined by the end user. This Anti-CD28 Antibody, clone 15E8 is validated for use in FC, FUNC for the detection of CD28. Research Sub Category Immunoglobulins & Immunology Research Category Inflammation & Immunology |
Linkage【联系】 | Replaces: CBL517P |
Physical form【外形】 | Please see lot specific datasheet for product formulation. We recommend that each laboratory determine an optimum working titre for use in its particular application. Format: Purified |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
Legal Information【法律信息】 | CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
antibody form【抗体形式】 | purified antibody |
antibody product type | primary antibodies |
clone【克隆】 | 15E8, monoclonal |
species reactivity | human |
should not react with | canine |
manufacturer/tradename | Chemicon® |
technique(s) | flow cytometry: suitable |
isotype【同位素/亚型】 | IgG1 |
NCBI accession no.【NCBI登记号】 | NM_006139.1 |
UniProt accession no.【UniProt登记号】 | P10747 |
shipped in【运输】 | wet ice |
Gene Information | human ... CD28(940) |
产品说明
Storage and Stability【储存及稳定性】 | For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C for up to one year. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | nwg |