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Anti-JAK2 (C-terminal) antibody produced in goat
| 产品编号： | 4102456 |
| 规格： | affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-JAK2 (C-terminal) antibody produced in goat
Tyrosine-protein kinase JAK2
Janus kinase 2 (a protein tyrosine kinase)
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Janus kinase 2 (JAK2) encodes a tyrosine kinase which belongs to the Jak family of protein kinases. The gene encoding this protein is localized on human chromosome 9p24. |
| Immunogen【免疫原】 | Peptide with sequence RVDQVRDNMAG, from the C-terminal region of the protein sequence according to AAC23653.1 |
| Biochem/physiol Actions【生化/生理作用】 | Janus kinase 2 (JAK2) plays an important role in the activities of cytokine receptors. Overexpression of JAK2 results in neuroblastoma. Mutations in the gene have been linked to primary resistance to PD-1 (anti-programmed death protein 1) blockade therapy. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin. |
产品性质
| biological source【生物来源】 | goat |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | human |
| technique(s) | indirect ELISA: suitable western blot: suitable |
| UniProt accession no.【UniProt登记号】 | O60674 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... JAK2(3717) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
