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Anti-Migration Inhibitory Factor Related Proteins 8 and 14 Antibody, clone AHN-17
产品别名
Anti-Migration Inhibitory Factor Related Proteins 8 and 14 Antibody, clone AHN-17
MRP-8 & 9, Myeloid-Related Protein-8 & 9, Calgranulin A & B, S100 Calcium-binding Protein A8 & A9, Leukocyte L1 cplx Light & Heavy Chain, Calprotectin
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Migration inhibitory factor-related proteins (MRP) -8 and -14 belong to the S-100 family of calcium binding proteins associated with myeloid cell differentiation. They are highly expressed in resting neutrophils, keratinocytes (particularly in psoriasis), in infiltrating tissue macrophages and on epithelial cells in active inflammatory disease. The heterogeneity of macrophage subpopulations in chronic or acute inflammation is reflected by different expression of MRP8 and MRP14. Phagocytes expressing MRP8 and MRP14 belong to the early infiltrating cells, while MRP8 alone is found in chronic inflammatory tissues. The partially antagonistic functions of MRP8, MRP14 and of the Ca2+-dependent MRP8/14 heterocomplex makes them versatile mediators. |
| Specificity【特异性】 | Migration Inhibitory Factor Releasing Proteins -8 and -14 |
| Immunogen【免疫原】 | Neutrophils |
| Application【应用】 | Research Sub Category Cytokines & Cytokine Receptors Immunocytochemistry on ethanol fixed cells Immunoblotting on un-reduced gels Optimal dilutions must be determined by the end user. Detect Migration Inhibitory Factor Related Proteins 8 & 14 using this Anti-Migration Inhibitory Factor Related Proteins 8 & 14 Antibody, clone AHN-17 validated for use in WB & IC. Research Category Inflammation & Immunology |
| Linkage【联系】 | Replaces: CBL269 |
| Physical form【外形】 | Format: Purified Purified immunoglobulin. Liquid in 0.02M Phosphate buffer, 0.25M NaCl with 0.1% sodium azide. |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
| Legal Information【法律信息】 | CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | AHN-17, monoclonal |
| species reactivity | human |
| manufacturer/tradename | Chemicon® |
| technique(s) | immunocytochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG1 |
| NCBI accession no.【NCBI登记号】 | NM_002964.3 |
| UniProt accession no.【UniProt登记号】 | P05109 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... S100A8(6279) |
产品说明
| Storage and Stability【储存及稳定性】 | Maintain at 2-8°C in undiluted aliquots for up to 6 months from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
