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Anti-PRDM14 Antibody
| 产品编号： | 4102608 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-PRDM14 Antibody
PR domain zinc finger protein 14, PR domain-containing protein 14
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | PR domain proteins (PRDMs) have been associated with many types of human cancers. PRDM14 was found to be up-regulated in breast cancer cells. The expression of PRDM14 to breast cancer cells actually increased cell proliferation and decreased the effect of chemotherapeutic drugs, while down-regulation of PRDM14 did the opposite. In addition to breast cancer, PRDM14 has recently been linked to non-small cell lung cancer development. PRDM14 also seems to play a role in the preservation of the self-renewal of human embryonic stem cells and transcriptional regulation. |
| Specificity【特异性】 | This antibody recognizes the N-terminus of PRDM14. |
| Immunogen【免疫原】 | GST-tagged recombinant protein corresponding to the N-terminus of human PRDM14. |
| Application【应用】 | This Anti-PRDM14 Antibody is validated for use in WB for the detection of PRDM14. |
| Quality【质量】 | Evaluated by Western Blot in human lung tissue lysate. Western Blot Analysis: A 1:1000 dilution of this antibody detected PRDM14 in 10 µg of human lung tissue lysate. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | rat, mouse, human |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_078780 |
| UniProt accession no.【UniProt登记号】 | Q9GZV8 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~62 kDa observed |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
