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Anti-Tyrosine Hydroxylase Antibody
产品别名
Anti-Tyrosine Hydroxylase Antibody
Tyrosine 3-hydroxylase, tyrosine 3-monooxygenase, tyrosine hydroxylase
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Tyrosine Hydroxylase plays an important role in the physiology of adrenergic neurons. It is the first and rate-limiting enzyme involved in the biosynthesis of the catecholamines Dopamine and Norepinephrine from tyrosine. TH is, therefore, a useful marker for dopaminergic and noradrenergic neurons. The enzymatic activity of TH requires ferrous ions as cofactors and is believed to be regulated by phosphorylation. At least four isoforms of human TH have been identified which result from alternative splicing. |
| Specificity【特异性】 | Cat. # AB9983 recognizes the C-terminus of Tyrosine Hydroxylase Reactivity with other species has not been determined. |
| Immunogen【免疫原】 | Recombinant protein Epitope: C-terminus |
| Application【应用】 | Anti-Tyrosine Hydroxylase Antibody detects level of Tyrosine Hydroxylase & has been published & validated for use in IH(P) & WB. Research Category Neuroscience Immunohistochemistry: 1:100 working dilutions were used on rat and mouse brain (paraffin embedded tissue). Research Sub Category Neurotransmitters & Receptors |
| Physical form【外形】 | Purified in 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3 Format: Purified Antigen Affinity Purified |
| Analysis Note【分析说明】 | Control Rat Brain lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | rat, mouse |
| technique(s) | immunohistochemistry: suitable (paraffin) western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_000351.2 |
| UniProt accession no.【UniProt登记号】 | P07101 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~ 58 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8ºC from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
