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Milli-Mark® Anti-CD54-FITC Antibody, clone 6.5B5
| 产品编号： | 4103046 |
| 规格： | clone 6.5B5, Milli-Mark®, from mouse |
| 包装规格： | 100 TESTS |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Milli-Mark® Anti-CD54-FITC Antibody, clone 6.5B5
Intercellular adhesion molecule 1, ICAM-1, Major group rhinovirus receptor
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.44 |
| General description【一般描述】 | The CD54 antigen is a single chain glycoprotein with a molecular mass of 90 kDa (Springer, 1990). It is the human intercellular adhesion molecule-1 (ICAM-1) belonging to the immunoglobulin supergene family. The ligand for ICAM-1 is LFA-1 (leucocyte function associated-1 protein) (Berendt, 1992). ICAM-1 is widely expressed on many cell types, although the degree of expression by unstimulated resting cells varies. As a cellular activation antigen the expression of ICAM-1 is up-regulated upon cell activation, being induced particularly in response to cytokines such as interleukin-1, tumor necrosis factor, and interferon- (Berendt, 1992; Wellicome, 1990; Thornhill, 1990). ICAM-1 might be a receptor for rhinovirus (Staunton, 1989). In rejecting kidneys the antibody stains all infiltrating cells strongly as well as glomerulus epithelium, endothelium on capillaries, large vessels, and mesangium (Waugh, 1989). |
| Specificity【特异性】 | Antibody recognizes Human CD54 antigen. |
| Immunogen【免疫原】 | TNF-activated human umbilical vein endothelial cells |
| Application【应用】 | Research Sub Category Immunoglobulins & Immunology Milli-Mark Anti-CD54-FITC Antibody, clone 6.5B5 is an antibody against CD54 for use in FC. Research Category Inflammation & Immunology |
| Quality【质量】 | Evaluated by flow cytometry using human lymphocytes |
| Physical form【外形】 | Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2. Protein A purified |
| Analysis Note【分析说明】 | Control Human Lymphocytes |
| Legal Information【法律信息】 | MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | FITC conjugate |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 6.5B5, monoclonal |
| species reactivity | human |
| manufacturer/tradename | Milli-Mark® |
| technique(s) | flow cytometry: suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NP_000192 |
| UniProt accession no.【UniProt登记号】 | P05362 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | 90 kDa (Springer, 1990) |
| Storage and Stability【储存及稳定性】 | Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
