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Milli-Mark® Anti-Tie2/TEK-PE Antibody, clone Ab33
产品别名
Milli-Mark® Anti-Tie2/TEK-PE Antibody, clone Ab33
Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, hTIE2, p140 TEK, CD202b
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin-like loops separated by three epidermal growth factor-like repeats that are connected to three fibronectin type III-like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations; the TIE2 signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. |
| Specificity【特异性】 | Antibody recognizes Human Tie2/TEK. |
| Immunogen【免疫原】 | Fusion protein corresponding to residues 1-745 of human Tie2/TEK with a C-terminal His6-tag purified from infected SF-9 cells. |
| Application【应用】 | Research Sub Category Growth Factors & Receptors Research Category Signaling Milli-Mark Anti-Tie2/TEK-PE Antibody, clone Ab33 is an antibody against Tie2/TEK for use in FC. |
| Quality【质量】 | Evaluated by flow cytometry using HUVEC cells. |
| Physical form【外形】 | Purified mouse monoclonal IgG1k conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA. Protein G Purified |
| Analysis Note【分析说明】 | Control HUVEC cells |
| Legal Information【法律信息】 | MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | PE |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | Ab33, monoclonal |
| species reactivity | human |
| manufacturer/tradename | Milli-Mark® |
| technique(s) | flow cytometry: suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NP_000450 |
| UniProt accession no.【UniProt登记号】 | Q02763 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... TEK(7010) |
产品说明
| Target description【目标描述】 | 126 kDa Calculated |
| Storage and Stability【储存及稳定性】 | Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
