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TWEAK Receptor human
| 产品编号： | 4103302 |
| 规格： | recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture |
| 包装规格： | 25 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
TWEAK Receptor human
TNF-related weak inducer of apoptosis receptor
TNFRSF12A
FGF-inducible 14
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | TWEAKR belongs to the TNFR superfamily of transmembrane proteins and contains a cytoplasmic "death domain," which can activated the cell′s apoptotic machinery. It is expressed in the spleen, thymus, peripheral blood lymphocytes, colon, and small intestine. Signal transduction by TWEAKR can be activated by either the membrane anchored or the soluble TWEAK. Recombinant soluble TWEAKR is a 53 amino acid polypeptide (5.6 kDa) comprising the entire extracellular domain of the full length TWEAKR protein |
| Biochem/physiol Actions【生化/生理作用】 | TWEAKR belongs to the TNFR superfamily of transmembrane proteins and contains a cytoplasmic "death domain," which can activated the cell′s apoptotic machinery. Recombinant soluble TWEAKR is a 53 amino acid polypeptide (5.6 kDa) comprising the entire extracellular domain of the full length TWEAKR protein |
| Sequence【序列】 | EQAPGTAPCS RGSSWSADLD KCMDCASCRA RPHSDFCLGC AAAPPAPFRL LWP |
| Physical form【外形】 | Lyophilized from 10 mM Sodium Phosphate, pH 7.5 + 50 mM NaCl. |
| Reconstitution【重悬】 | Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8℃ for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20℃ to -80℃. |
产品性质
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥98% (HPLC) ≥98% (SDS-PAGE) |
| form【形式】 | lyophilized |
| potency【效能】 | 1.0-3.0 μg/mL ED50 |
| mol wt【分子量】 | 5.6 kDa |
| packaging【包装】 | pkg of 25 μg |
| technique(s) | cell culture | mammalian: suitable |
| impurities【杂质】 | <0.1 EU/μg endotoxin, tested |
| color【颜色】 | white |
| UniProt accession no.【UniProt登记号】 | Q9NP84 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... TNFRSF12A(51330) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
