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α-Spinasterol
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4103799 | 10 MG | 5970 |
产品别名
481-18-5
α-Spinasterol
α-Spinasterin
Hitodesterol
Spinasterol
(E)-5α-Stigmasta-7,22-dien-3β-ol
5α-Stigmasta-7,22-dien-3β-ol
Bessisterol
(3β,5α,22E)-Stigmasta-7,22-dien-3-ol
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C29H48O |
| Molecular weight | 412.69 |
| MDL number | MFCD00200554 |
| General description【一般描述】 | This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG |
| Biochem/physiol Actions【生化/生理作用】 | α-Spinasterol is a blood-brain barrier-permeable and orally active plant phytosterol with antioxidant, anticonvulsant (0.1-1 mg/kg i.p. in mice), antidepressant (1-2 mg/kg i.p. in mice) and anti-inflammatory (0.001-1 mg/kg, i.p. or 1-10 mg/kg, i.g. in mice) properties, as well as antinociceptive efficacy via dual actions against transient receptor potential vanilloid 1 (TrpV1; IC50/Emax = 1.4 μM/67% against 2 nM RTX for binding mouse spinal cord membranes; IC50/Emax = 40 μM/62% against 20 μM capsaicin-induced mouse spinal cord synaptosomes Ca2+ influx) and cyclooxygenases (IC50 = 16.17 μM/COX1 and 7.76μM/COX2). a-spinasterol can directly affect membrane structure and packing in a manner similar to cholesterol, both a-spinasterol and stitosterol are reported to lower plasma/liver cholesterol levels and increase fecal cholesterol excretion when supplemented in daily diet (1%) in mice in vivo. |
| Legal Information【法律信息】 | phyproof is a registered trademark of PhytoLab GmbH & Co. KG |
产品性质
| grade【等级】 | primary reference standard |
| product line【产品线】 | phyproof® Reference Substance |
| Assay【测定】 | ≥90.0% (HPLC) |
| form【形式】 | solid |
| manufacturer/tradename | PhytoLab |
| SMILES string | C[C@@]12[C@](CC[C@]2([H])[C@H](C)/C=C/[C@@H](CC)C(C)C)([H])C3=CC[C@@]4([H])C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC1 |
| InChI | 1S/C29H48O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h8-9,11,19-23,25-27,30H,7,10,12-18H2,1-6H3/b9-8+/t20-,21-,22+,23+,25-,26+,27+,28+,29-/m1/s1 |
| InChI key | JZVFJDZBLUFKCA-FXIAWGAOSA-N |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
