Anti-ARX Antibody, clone 11F6.2

32160702

NA.41

Aristaless-related homeobox protein (ARX) is a transcription factor that plays an important role in the development of the brain, testis, and pancreas. The gene targets and nuclear associations of ARX are less clear, although it has been demonstrated that ARX interacts with the Pax4 promoter. However, over fifty ARX mutations have been identified and the resultant phenotypes have been well studied. ARX mutations are X-linked and lead to various syndromes including X-linked West syndrome; X-linked myoclonic epilepsy; Partington syndrome; and X-linked mental retardation.

GST-tagged recombinant protein corresponding to human ARX.

Immunohistochemistry Analysis: A 1:1,000 dilution from a reprsentative lot detected ARX in human brain tissue.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience
Detect ARX using this Anti-ARX Antibody, clone 11F6.2 validated for use in Western Blotting, IHC(P).

Evaluated by Western Blot in human pancreas tissue lysate.

Western Blot Analysis: 2 µg/mL of this antibody detected ARX in 200 µg of human pancreas tissue lysate.

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified

Control
Human pancreas tissue lysate.

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

100

mouse

purified immunoglobulin

primary antibodies

11F6.2, monoclonal

human

immunohistochemistry: suitable (paraffin)
western blot: suitable

IgG1κ

NP_620689

Q96QS3

wet ice

human ... ARX(170302)

~58 kDa observed. An uncharacterized band may be observed at ~23 kDa in some tissue lysates.

Stable for 1 year at 2-8°C from date of receipt.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

12 - Non Combustible Liquids

WGK 1