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Anti-ATP2C1 Antibody
| 产品编号： | 4105211 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-ATP2C1 Antibody
Calcium-transporting ATPase type 2C member 1, ATPase 2C1, ATP-dependent Ca(2+) pump PMR1, ATP2C1
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Calcium-transporting ATPase type 2C member 1 (ATP2C1) is a member of the cation transport ATPase (P-type) (TC 3.A.3) family. ATP2C1 catalyzes the hydrolysis of ATP coupled with the transport of the calcium from the cytosol to the Golgi lumen. It may also play an important role as a key regulator of insulin-like growth factor receptor (IGF1R) processing in tumor progression in basal breast cancers. It is found in most tissues except colon, thymus, spleen and leukocytes. |
| Specificity【特异性】 | This antibody can recognize the three longest isoforms at ~101 kDa, ~103 kDa, and ~105 kDa. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human ATP2C1. |
| Application【应用】 | Anti-ATP2C1 Antibody is a highly specific rabbit polyclonal antibody, that targets Calcium-transporting ATPase type 2C member 1 & has been tested in western blotting & IHC. Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected ATP2C1 in mouse brain tissue. Research Category Neuroscience Research Sub Category Neurodegenerative Diseases |
| Quality【质量】 | Evaluated by Western Blotting/Peptide Inhibition Assay in mouse brain tissue lysate. Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected ATP2C1 in 15 µg of mouse brain tissue lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. Antigen Affinity Purified |
| Analysis Note【分析说明】 | Control Mouse brain tissue lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | mouse |
| species reactivity (predicted by homology) | human (immunogen homology) |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| UniProt accession no.【UniProt登记号】 | P98194 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... ATP2C1(27032) |
产品说明
| Target description【目标描述】 | ~180 kDa observed. Uniprot describes 6 isoforms ranging between ~97 kDa and ~105 kDa Uncharacterized bands may appear in some lysate(s). |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
