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Anti-CASP10 (C-terminal) antibody produced in rabbit
产品别名
Anti-CASP10 (C-terminal) antibody produced in rabbit
ALPS2
Flice2
Mch4
产品性质
biological source【生物来源】 | rabbit |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 57 kDa |
species reactivity (predicted by homology) | human |
concentration【浓度】 | 0.5 mg/mL |
technique(s) | western blot: 1 μg/mL |
NCBI accession no.【NCBI登记号】 | NM_032977 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... CASP10(57396) |
基本信息
General description【一般描述】 | This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. |
Immunogen【免疫原】 | Synthetic peptide directed towards the c-terminal region of Human CASP10 |
Sequence【序列】 | Synthetic peptide located within the following region: QSLCNHLKKLVPRHEDILSILTAVNDDVSRRVDKQGTKKQMPQPAFTLRK |
Physical form【外形】 | Supplied at 0.5 mg/ml in phosphate-buffered saline, 0.09% sodium azide |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | nwg |