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Anti-DPPA-2 Antibody, clone 6C1.2
产品别名
Anti-DPPA-2 Antibody, clone 6C1.2
Pluripotent embryonic stem cell-related gene 1 protein, developmental pluripotency associated 2
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | DPPA-2 (developmental pluripotency associated-2) is a novel Oct-4-related protein that is localized to the nucleus of mouse fetal germ cells. DPPA-2 has binding sites for both POU and Sox-2 protein domains and is expressed primarily in the developing germ line following gastrulation. These associations suggest that this protein participates in a very strong supportive role in maintaining cell pluripotentiality. In addition to its role as a pluripotency marker, more recent research using cancer cells suggests that DPPA-2 may also act as an embryo-cancer antigen—pointing to the presence of abnormal cell growth and the formation of cancerous cells. |
| Specificity【特异性】 | Reactivity with other species has not been tested. This monoclonal antibody recognizes the mouse DPPA-2 protein. |
| Immunogen【免疫原】 | Full length recombinant mouse DPPA-2 protein. |
| Application【应用】 | Research Sub Category Pluripotent & Early Differentiation Research Category Stem Cell Research This Anti-DPPA-2 Antibody, clone 6C1.2 is validated for use in WB for the detection of DPPA-2. |
| Quality【质量】 | (Based upon representative data from a previous lot). Western Blotting: Recommended working concentration is 2 µg/mL. |
| Physical form【外形】 | Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4) and 150 mM NaCl with 0.05% sodium azide. Format: Purified Protein G Purified |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | 6C1.2, monoclonal |
| species reactivity | mouse |
| technique(s) | western blot: suitable |
| input | sample type: mouse embryonic stem cell(s) |
| isotype【同位素/亚型】 | IgG2aκ |
| UniProt accession no.【UniProt登记号】 | Q7Z7J5 Q9CWH0 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~34 kDa |
| Storage and Stability【储存及稳定性】 | Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
