Anti-GABA A Receptor β 2,3 Chain Antibody, clone BD17

32160702

NA.41

Gamma-aminobutyric acid type A (GABAA) receptors are members of the neurotransmitter ligand-gated ion channels that mediate neuronal inhibition on binding GABA. The effects of GABA on GABAA receptors are modulated by a range of therapeutically important drugs, including barbiturates, anaesthetics and benzodiazepines.

Reacts with the β-chain of the GABAA receptor.

Purified GABA/benzodiazepine receptor from bovine cortex
Epitope: Extracellular domain of the beta2 & beta3 subunits of the GABAA receptor

Immunohistochemistry:
A 10-20 μg/mL concetration of a previous lot was used in IH.

Immunoprecipitation:
A previous lot of this antibody was used in IP.

Western blot:
5-20 µg/mL. Recognizes a 55 kDa band corresponding to the beta chain of the GABAA receptor.

Optimal working dilutions must be determined by end user.
Detect GABA A Receptor β 2 using this Anti-GABA A Receptor β 2, 3 Chain Antibody, clone BD17 validated for use in IH, IP & WB.

Evaluated by Western Blot on mouse brain membrane lysates.

Western Blot:
1:500 dilution of this antibody detected GABA A Receptor β 2,3 Chain on 10 μg of mouse brain membrane lysates.

Replaces: AB5952

Format: Purified
Protein A purified
Purified mouse monoclonal IgG1 liquid in buffer containing 10 mM potassium phosphate buffer pH 7.4 with 150 mM NaCl

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

100

mouse

purified immunoglobulin

primary antibodies

BD17, monoclonal

monkey, mouse, feline, bovine

human, rat

Chemicon^®

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

IgG1

NM_000813.2

P47870

dry ice

human ... GABRB2(2561)

55 kDa

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