Anti-GABA(A)R BETA 1 Protein Antibody, clone N96/55

32160702

NA.41

GABA(A)R, beta-1 is a subunit of the GABA receptor. GABA receptors belong to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid or GABA is the major inhibitory neurotransmitter in the vertebrate brain. GABA mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. GABA receptors play an important role in transmembrane ion transport, excitability and synaptic transmission.

Other homologies: Human (95% sequence homology).
This antibody does not cross react with GABA-A-R, Beta 2 Protein or GABA-A-R, Beta 3 Protein.

Fusion protein corresponding to mouse GABA(A)R, BETA 1.

Research Sub Category
Signaling Neuroscience
Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected GABA(A)R, BETA 1 Protein in rat olfactory lobe tissue.

Western Blot Analysis: A representative lot detected GABA(A)R, BETA 1 Protein in rat brain membrane tissue lysate.

Immunohistochemistry Analysis: A representative lot detected GABA(A)R, BETA 1 Protein in rat hippocampus tissue.
Research Category
Neuroscience
This GABA(A)R antibody is validated for use in IHC & WB for the detection of the GABA(A)R protein.

Evaluated by Immunohistochemistry in rat hippocampus tissue.

Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected GABA(A)R, BETA 1 Protein in rat hippocampus tissue.

Format: Purified
Purified monoclonal mouse IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Protein G Purified

Control
Rat hippocampus tissue

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

100

mouse

purified immunoglobulin

primary antibodies

N96/55, monoclonal

rat, mouse

immunohistochemistry: suitable
western blot: suitable

IgG1κ

NP_032095

P50571

wet ice

~55 kDa observed

Stable for 1 year at 2-8°C from date of receipt.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

12 - Non Combustible Liquids

WGK 1