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Anti-hGITR Antibody, clone 108-17
产品别名
Anti-hGITR Antibody, clone 108-17
Tumor necrosis factor receptor superfamily member 18, Activation-inducible TNFR family receptor, Glucocorticoid-induced TNFR-related protein, CD357
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Glucocorticoid-induced TNFR-related protein (hGITR) is also called Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), Activation-inducible TNFR family receptor (AITR) and CD357. hGITR is a receptor for TNFSF18 and is activated by NF-kappa-B through the TRAF2/NIK pathway. hGITR is thought to be involved in activated T-lymphocyte and endothelial cell interactions, as well as regulation of T-cell receptor-mediated cell death. hGITR is expressed in lymph node, peripheral blood leukocytes and at low levels in the spleen. |
| Immunogen【免疫原】 | Recombinant protein corresponding to human hGITR. |
| Application【应用】 | Western Blotting Analysis: 1.0 µg/mL from a representative lot detected hGITR in 10 µg of mouse lymph node, rat spleen, and rat thymus tissue lysate. Anti-hGITR Antibody, clone 108-17 is a highly specific mouse monoclonal antibody & that targets GITR & has been tested in western blotting. Research Sub Category Immunoglobulins & Immunology Research Category Inflammation & Immunology |
| Quality【质量】 | Evaluated by Western Blotting in human spleen tissue lysate. Western Blotting Analysis: 1.0 µg/mL of this antibody detected hGITR in 10 µg of human spleen tissue lysate. |
| Physical form【外形】 | Purified mouse monoclonal IgG1κ in buffer containing PBS with 0.05% sodium azide. Format: Purified Protein A purified |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 108-17, monoclonal |
| species reactivity | human, mouse, rat |
| technique(s) | western blot: suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NP_004186 |
| UniProt accession no.【UniProt登记号】 | Q9Y5U5 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~ 26 kDa observed. Multiple bands can be observed due to GITR being a monomer & homeodimer in some lysates. Uncharacterized band(s) may appear in some lysates. |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
