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Anti-Ido1, clone 8G11 Antibody
产品别名
Anti-Ido1, clone 8G11 Antibody
Ido1, Indoleamine 2,3-dioxygenase 1, IDO-1, Indoleamine-pyrrole 2,3-dioxygenase
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Indoleamine 2,3-dioxygenase (IDO) is an enzyme that is responsible for converting tryptophan to kynurenines. IDO is expressed by a wide variety of tissues and can be upregulated by interferon gamma. IDO modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response. IDO may be involved in the suppression of the immune response to tumours and blocking the IDO pathway may be a potential target for immunotherapy. |
| Specificity【特异性】 | This antibody does not cross react with Ido2. |
| Immunogen【免疫原】 | Recombinant protein corresponding to mouse Ido1. |
| Application【应用】 | Western Blotting Analysis: A representative lot detected Ido1 in splenic dendric cells from WT or KO mouse tissue lysate (Oberdan Leo, Universite Libre de Bruxelles). Flow Cytometry Analysis: A representative lot detected Ido1 in splenic dendric cells from mouse (Oberdan Leo, Universite Libre de Bruxelles). Anti-Ido1, clone 8G11 Antibody is an antibody against Ido1 for use in Western Blotting, Flow Cytometry. |
| Quality【质量】 | Evaluated by Western Blotting in Ido1-Flag tag transfected HEK293T cell lysate. Western Blotting Analysis: 0.5 µg/mL of this antibody detected Ido1 in 10 µg of Ido1-Flag tag transfected HEK293T cell lysate. |
| Physical form【外形】 | Protein G Purified Format: Purified |
| Other Notes【其他说明】 | Concentration: Please refer to lot specific datasheet. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 8G11, monoclonal |
| species reactivity | mouse |
| technique(s) | flow cytometry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG2aκ |
| NCBI accession no.【NCBI登记号】 | NP_002155 |
| UniProt accession no.【UniProt登记号】 | P14902 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... IDO1(3620) |
产品说明
| Target description【目标描述】 | ~44 kDa observed. Uncharacterized band(s) may appear in some lysates. |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
