您的位置:首页 > 产品中心 > Anti-KEAP1, clone 7G4B10 Antibody
Anti-KEAP1, clone 7G4B10 Antibody
![](/image/daily/2022/05/17/070901_836584_image_776645.jpg)
产品别名
Anti-KEAP1, clone 7G4B10 Antibody
Kelch-like ECH-associated protein 1, Cytosolic inhibitor of Nrf2, INrf2, Kelch-like protein 19, KEAP1
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Kelch-like ECH-associated protein 1, also known as Cytosolic inhibitor of Nrf2 or INrf2 or Kelch-like protein 19, and encoded by the gene name KEAP1 or INRF2 or KLHL19, acts as a substrate adapter protein for the E3 ubiquitin ligase complex and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome. KEAP1 shuttles between the cytoplasm and the nucleus and is widely expressed with high levels found in skeletal muscle. |
Immunogen【免疫原】 | Purified recombinant fragment of human KEAP1 expressed in E. Coli |
Application【应用】 | Research Sub Category Apoptosis - Additional Research Category Apoptosis & Cancer Anti-KEAP1, clone 7G4B10 Antibody is an antibody against KEAP1 for use in IHC, flow cytometry & ELISA. Flow Cytometry Analysis: A 1:200-400 dilution from a representative lot detected KEAP1 in HeLa cells. ELISA: A representative lot detected control Antigen (100 ng) and Antigen (10 ng, 50 ng, 100 ng) in ELISA (Direct). |
Quality【质量】 | Immunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected KEAP1 in bladder cancer and cerebellum tissues. |
Physical form【外形】 | Purified mouse monoclonal in PBS containing up to 0.1% sodium azide and 0.5% protein stabilizer. Format: Purified Protein G Purified |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
antibody form【抗体形式】 | purified antibody |
antibody product type | primary antibodies |
clone【克隆】 | 7G4B10, monoclonal |
species reactivity | human |
technique(s) | ELISA: suitable flow cytometry: suitable immunohistochemistry: suitable |
UniProt accession no.【UniProt登记号】 | Q14145 |
shipped in【运输】 | wet ice |
Gene Information | human ... KEAP1(9817) |
产品说明
Target description【目标描述】 | 70 kDa calculated |
Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |