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Anti-MLC-2 Antibody, clone 19D3.1
产品别名
Anti-MLC-2 Antibody, clone 19D3.1
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform, MLC-2, MLC-2v
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Myosin light chain 2 (MLC2), also known as myosin regulatory light chain (MRLC), RLC, or LC20, has several isoforms and is a component of myosin, which is made up of two heavy chains and four light chains. MLC2 is involved in smooth muscle contraction, stress fiber assembly, and cytokinesis. MLC2 defects can cause of familial hypertrophic cardiomyopathy type 10 (CMH10). |
Specificity【特异性】 | Other homologies: Mouse 92% sequence homologies. |
Immunogen【免疫原】 | GST-tagged recombinant protein corresponding to human MLC-2. |
Application【应用】 | Research Category Cell Structure Detect Myosin using this mouse monoclonal antibody, Anti-MLC-2 Antibody, clone 19D3.1 validated for use in western blotting & IHC. Research Sub Category ECM Proteins Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected MLC-2 in human cardiac myocyte and in rat skeletal muscle tissues. |
Quality【质量】 | Evaluated by Western Blotting in human skeletal muscle tissue lysate. Western Blotting Analysis: A 1:2,000 dilution from a representative lot detected MLC-2 in 10 µg of human skeletal muscle tissue lysate. |
Physical form【外形】 | Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Format: Purified Protein G Purified |
Analysis Note【分析说明】 | Control Human skeletal muscle tissue lysate. |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | 19D3.1, monoclonal |
species reactivity | human, rat |
technique(s) | immunohistochemistry: suitable western blot: suitable |
isotype【同位素/亚型】 | IgG1κ |
NCBI accession no.【NCBI登记号】 | NP_000423 |
UniProt accession no.【UniProt登记号】 | P10916 |
shipped in【运输】 | wet ice |
Gene Information | human ... MYL2(4633) |
产品说明
Target description【目标描述】 | ~19 kDa observed |
Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |