您的位置：首页 > 产品中心 > Anti-MMP-13 Antibody, clone LIPCO IID1
Anti-MMP-13 Antibody, clone LIPCO IID1
| 产品编号： | 4110294 |
| 规格： | clone LIPCO IID1, Chemicon®, from mouse |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-MMP-13 Antibody, clone LIPCO IID1
Collagenase-3
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| Specificity【特异性】 | It recognizes proteins of ~60 kDa and ~48 kDa which are identified as pro (latent) and activate forms of matrix metalloproteinase-13 (MMP-13; also known as Collagenase-3). Antibody shows no cross-reactivity with the pro and active forms of other MMPs. Human collagenase-3 (MMP13) is a recently identified member of the matrix metalloproteinase (MMP) family that is expressed in breast carcinomas and in articular cartilage from arthritic patients. The MMP-13 gene has been isolated and characterized. This gene is composed of 10 exons and 9 introns and spans over 12.5 kb. The overall organization of the collagenase-3 gene is similar to that of other MMP genes clustered at chromosome 11q22, including fibroblast collagenase (MMP-1), matrilysin (MMP-7), and macrophage metalloelastase (MMP-12), but is more distantly related to genes coding for stromelysin-3 (MMP-11), gelatinase-A (MMP-2), and gelatinase-B (MMP-9), which map outside of this gene cluster. Cellular Localization: Cytoplasmic |
| Immunogen【免疫原】 | Rat MMP-13 from BC-1 cells. |
| Application【应用】 | Research Category Cell Structure Western Blotting (Lyons, 1991; Lyons, 1993): 1:200-1:400 at room temperature for 2 hours. Immunofluorescence Optimal working dilutions must be determined by end user. Anti-MMP-13 Antibody, clone LIPCO IID1 is an antibody against MMP-13 for use in WB. Research Sub Category MMPs & TIMPs |
| Physical form【外形】 | Format: Purified |
| Analysis Note【分析说明】 | Control POSITIVE CONTROL: Conditioned, serum-free medium from (PMA-treated) rat fibrosarcoma cells or rat keratinocyte CCL-4. |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
| Legal Information【法律信息】 | CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | LIPCO IID1, monoclonal |
| species reactivity | rat, mouse |
| manufacturer/tradename | Chemicon® |
| technique(s) | western blot: suitable |
| isotype【同位素/亚型】 | IgG1 |
| NCBI accession no.【NCBI登记号】 | NM_002427.2 |
| UniProt accession no.【UniProt登记号】 | P45452 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... MMP13(4322) |
产品说明
| Storage and Stability【储存及稳定性】 | Maintain at 2-8°C in undiluted aliquots for up to 12 months. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
