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Anti-Mouse IgG IgA IgM (H+L), F(ab′)2 fragment, highly cross adsorbed-Alkaline Phosphatase antibody produced in goat
产品编号: | 4110443 |
规格: | affinity isolated antibody, buffered aqueous solution |
包装规格: | 500 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Mouse IgG IgA IgM (H+L), F(ab′)2 fragment, highly cross adsorbed-Alkaline Phosphatase antibody produced in goat
Alk Phos
ALP
基本信息
NACRES | NA.46 |
General description【一般描述】 | Immunoglobulins (Igs) or antibodies are Y-shaped molecules which are the secreted form of the B-cell receptor. Igs are composed of two heavy and two light chains. An immunoglobulin possesses variable (V) domains that bind to antigens and constant (C) domains that bind to effector molecules. Limited digestion using papain cleaves the antibody into three fragments, two of which are identical and contain the antigen-binding activity. They are known as fragment antigen binding (Fab) fragments. The third fragment does not possess antigen-binding activity and is known as fragment crystallizable (Fc). It interacts with cells and effector molecules. Pepsin cleaves the carboxy-terminal side of the disulfide bonds in the general region of the antibody and this gives rise to the F(ab′)2 fragment. The two antigen-binding arms of the antibody are linked in this fragment. There are five classes of immunoglobulins- IgM, IgA, IgG, IgD and IgE, classified based on their C regions. |
Specificity【特异性】 | This product was prepared from monospecific antiserum by immunoaffinity chromatography using Mouse antigens coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities, pepsin digestion and chromatographic separation. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Alkaline Phosphatase and Anti-Goat Serum. No reaction was observed against Anti-Pepsin, Anti-Goat IgG F(c) or Human Serum Proteins. This reagent is suitable for the detection of all Mouse immunoglobulin subclasses and chain combinations. |
Immunogen【免疫原】 | Mouse IgG IgA and IgM whole molecule |
Physical properties【物理属性】 | Antibody format: IgG F(ab′)2 |
Physical form【外形】 | Supplied in 0.05 M Tris Chloride, 0.15M Sodium Chloride, 0.001M Magnesium Chloride, 0.0001M Zinc Chloride, 50% (v/v) Glycerol; pH 8.0 with 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | goat |
conjugate【偶联物】 | alkaline phosphatase conjugate |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | secondary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
species reactivity | mouse |
concentration【浓度】 | 1.0 mg/mL |
technique(s) | immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | 2-8℃ |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |