Anti-NEFM antibody produced in goat

MFCD00164708

NA.41

NEFM (neurofilament, medium polypeptide) is a highly available cytoskeleton intermediate filament (IF) protein in post-mitotic neurons. It is mapped to human chromosome 8q21. It is abundantly present in the nervous system. In human, the protein has 13 carboxy-terminal domains with phosphorylation sites.

Peptide with sequence CQASHITVERKDYLK, from the internal region of the protein sequence according to NP_005373.2; NP_001099011.1.

Anti-NEFM antibody produced in goat is suitable for indirect ELISA and western blot analysis.

NEFM (neurofilament, medium polypeptide) protein is involved in the axonal transport and neuronal cell apoptosis. Phosphorylation of NEFM allows the association between NEFM and microtubules. Deregulated phosphorylation of NEFM is associated with Alzheimer disease (AD). From gene mutation analysis, it has been predicted that NEFM may be a susceptibility factor for the Parkinson′s disease (PD).

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Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

100

goat

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

rat, mouse, human

indirect ELISA: suitable
western blot: suitable

P07197

dry ice

−20℃

human ... NEFM(4741)

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WGK 2