您的位置：首页 > 产品中心 > Anti-NKX6-1, (N-terminal) antibody produced in rabbit
Anti-NKX6-1, (N-terminal) antibody produced in rabbit
产品别名
Anti-NKX6-1, (N-terminal) antibody produced in rabbit
Anti-NKX6A
鍩烘湰淇℃伅
| NACRES | NA.41 |
| Immunogen【鍏嶇柅鍘煛� | Synthetic peptide directed towards the N terminal region of human NKX6-1 |
| Biochem/physiol Actions【鐢熷寲/鐢熺悊浣滅敤】 | NKX6-1 is the transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. NKX6-1 is involved in transcriptional regulation in islet beta cells. Binds to the insulin promoter and is involved in regulation of the insulin gene. Together with NKX2-2 and IRX3, NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. NKX6-1 belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals.In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-300 U66797.1 1-300 301-307 AC096766.3 119394-119400 c 308-676 U66797.1 308-676 677-849 U66798.1 7-179 850-1116 U66799.1 7-273 |
| Sequence【搴忓垪】 | Synthetic peptide located within the following region: MLAVGAMEGTRQSAFLLSSPPLAALHSMAEMKTPLYPAAYPPLPAGPPSS |
| Physical form【澶栧舰】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
浜у搧鎬ц川
| biological source【鐢熺墿鏉ユ簮】 | rabbit |
| Quality Level【璐ㄩ噺姘村钩】 | 100 |
| conjugate【鍋惰仈鐗� | unconjugated |
| antibody form【鎶椾綋褰㈠紡】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【鍏嬮殕】 | polyclonal |
| form【褰㈠紡】 | buffered aqueous solution |
| mol wt【鍒嗗瓙閲彙� | 38 kDa |
| species reactivity | mouse, rabbit, pig, dog, human, bovine, horse, rat |
| concentration【娴撳害】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI鐧昏鍙贰� | NM_006168 |
| UniProt accession no.【UniProt鐧昏鍙贰� | P78426 |
| shipped in【杩愯緭】 | wet ice |
| storage temp.【鍌ㄥ瓨娓╁害】 | −20鈩� |
| Gene Information | human ... NKX6-1(4825) |
浜у搧璇存槑
| Disclaimer【鍏嶈矗澹版槑】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
瀹夊叏淇℃伅
| Storage Class Code【鍌ㄥ瓨鍒嗙被浠ｇ爜】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
