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Anti-NOTCH2 (Cleaved-Ala1734) antibody produced in rabbit
产品别名
Anti-NOTCH2 (Cleaved-Ala1734) antibody produced in rabbit
NOTCH2
NOTC2
Motch B
Neurogenic locus notch homolog protein 2 precursor
NTC2
鍩烘湰淇℃伅
| NACRES | NA.41 |
| General description【涓�鑸弿杩啊� | The NOTCH2 (notch 2) gene is mapped to human chromosome 1p12. Anti-NOTCH2 (cleaved-Ala1734) antibody detects endogenous levels of fragment of activated NOTCH2 (cleaved-Ala1734) protein. |
| Immunogen【鍏嶇柅鍘煛� | The antiserum was produced against synthesized peptide derived from human NOTCH2. Immunogen Range: 1715-1764 |
| Biochem/physiol Actions【鐢熷寲/鐢熺悊浣滅敤】 | The NOTCH2 (notch2) gene is known to be involved in the proliferation and cell cycle progression in cancer cells. Upregulation of the gene is observed in salivary adenoid cystic carcinoma, and hepatocellular carcinoma. Deletion of NOTCH2 offers tumor cells resistance to chemotherapeutic agents such as 5-fluorouracil. NOTCH2 plays an important role in the regulation of liver development. The NOTCH2 gene is associated with the development of diabetic nephropathy. |
| Features and Benefits【鐗圭偣鍜屼紭鍔俊� | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【澶栧舰】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
浜у搧鎬ц川
| biological source【鐢熺墿鏉ユ簮】 | rabbit |
| Quality Level【璐ㄩ噺姘村钩】 | 100 |
| conjugate【鍋惰仈鐗� | unconjugated |
| antibody form【鎶椾綋褰㈠紡】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【鍏嬮殕】 | polyclonal |
| form【褰㈠紡】 | buffered aqueous solution |
| mol wt【鍒嗗瓙閲彙� | antigen 79 kDa |
| species reactivity | human, mouse, rat |
| concentration【娴撳害】 | ~1 mg/mL |
| technique(s) | ELISA: 1:10000 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI鐧昏鍙贰� | Q04721 |
| UniProt accession no.【UniProt鐧昏鍙贰� | Q04721 |
| shipped in【杩愯緭】 | wet ice |
| storage temp.【鍌ㄥ瓨娓╁害】 | −20鈩� |
| Gene Information | human ... NOTCH2(4853) |
浜у搧璇存槑
| Disclaimer【鍏嶈矗澹版槑】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
瀹夊叏淇℃伅
| Storage Class Code【鍌ㄥ瓨鍒嗙被浠ｇ爜】 | 12 - Non Combustible Liquids |
| WGK | nwg |
