您的位置：首页 > 产品中心 > Anti-NOVA1 antibody produced in rabbit
Anti-NOVA1 antibody produced in rabbit
产品别名
Anti-NOVA1 antibody produced in rabbit
Anti-neuro-oncological ventral antigen 1
Anti-Nova-1
浜у搧鎬ц川
| biological source【鐢熺墿鏉ユ簮】 | rabbit |
| Quality Level【璐ㄩ噺姘村钩】 | 100 |
| conjugate【鍋惰仈鐗� | unconjugated |
| antibody form【鎶椾綋褰㈠紡】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【鍏嬮殕】 | polyclonal |
| form【褰㈠紡】 | buffered aqueous solution |
| mol wt【鍒嗗瓙閲彙� | 52 kDa |
| species reactivity | dog, guinea pig, mouse, rat, horse, rabbit, bovine, human |
| concentration【娴撳害】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI鐧昏鍙贰� | NP_006480 |
| UniProt accession no.【UniProt鐧昏鍙贰� | A8K603 |
| shipped in【杩愯緭】 | wet ice |
| storage temp.【鍌ㄥ瓨娓╁害】 | −20鈩� |
| Gene Information | human ... NOVA1(4857) |
鍩烘湰淇℃伅
| General description【涓�鑸弿杩啊� | NOVA1 (Neuro-oncological ventral antigen 1) is a neuron-specific nuclear RNA-binding protein expressed in brain, specifically in hippocampus, hypothalamus, cingulate cortex, and medial habenular nucleus. |
| Immunogen【鍏嶇柅鍘煛� | Synthetic peptide directed towards the C terminal region of human NOVA1 |
| Application【搴旂敤】 | Anti-NOVA1 antibody produced in rabbit is suitable for western blot analysis. |
| Biochem/physiol Actions【鐢熷寲/鐢熺悊浣滅敤】 | NOVA1 (Neuro-oncological ventral antigen 1) is associated with several post-transcriptional regulation of RNA metabolism including RNA splicing, editing to transport, localization, and degradation. It may be involved in mediating neuronal responsiveness. It encodes a protein which has homology with the RNA-binding protein hnRNP K, the yeast splicing protein MER1. Since, it has some homology with hnRNP K, it may influence the regulation of RNA splicing or metabolism in developing neurons. The importance of NOVA1 as prognostic marker has been reported in HCC (Hepatocellular carcinoma). Alteration in gene causes a disorder associated with breast cancer and motor dysfunction i.e. paraneoplastic opsoclonus myoclonus ataxia (POMA). |
| Sequence【搴忓垪】 | Synthetic peptide located within the following region: SKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGVRAANPQKVG |
| Physical form【澶栧舰】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
浜у搧璇存槑
| Disclaimer【鍏嶈矗澹版槑】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
瀹夊叏淇℃伅
| Storage Class Code【鍌ㄥ瓨鍒嗙被浠ｇ爜】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
