Anti-NOX1 (N-terminal) antibody produced in rabbit

NA.41

Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 1 (NOX1) belongs to the family of NADPH oxidases. It is abundantly expressed in colon, primarily in differentiated epithelial cells. NOX1 has two cytosolic regulators, NOXA1 and NOXO1 as well as Ras-related protein Rac1.

synthetic peptide corresponding to the N-terminal of human NOX1 isoform long (NOX1L). The corresponding sequence is identical in human NOX1 isoform long variant (NOX1LV) and highly conserved in mouse and rat NOX1 (76% sequence identity).

Anti-NOX1 (N-terminal) antibody produced in rabbit has been used in immunoblotting and immunohistochemistry.

Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 1 (NOX1) catalyzes the generation of superoxide ion. It is mitogenic and a potent trigger of the angiogenic switch, increasing the vascularity of tumors and inducing molecular markers of angiogenesis.. NOX1 promotes neurotoxic activation of microglia suggesting, that they play a central role during neuroinflammatory states and in amyotrophic lateral sclerosis (ALS).

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

rabbit

200

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

antigen ~72 kDa

human

~1.5 mg/mL

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 5-10 μg/mL using using human colon
western blot: 1.5-3.0 μg/mL using using HT29 cell extracts

Q9Y5S8

dry ice

−20鈩�

human ... NOX1(27035)

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12 - Non Combustible Liquids