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Anti-Numb Antibody, clone 6G10.1
产品别名
Anti-Numb Antibody, clone 6G10.1
Protein numb homolog, h-Numb, S171
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Numb plays a key role in neurogenesis and in cell fate decisions. It maintains self-renewal properties in neural progenitor cells, which are also called radial glial cells (RGCs). It functions through inhibition of Notch signaling. Additionally, it is suggested to mediate local repair in brain ventricular wall damage. |
| Specificity【特异性】 | This antibody recognizes Numb isoforms 1 and 2. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human Numb isoforms 1 and 2. |
| Application【应用】 | Detect Numb using this Anti-Numb Antibody, clone 6G10.1 validated for use in WB & IC. Research Category Neuroscience Research Sub Category Developmental Neuroscience Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected Numb in HeLa and A431 cells. |
| Quality【质量】 | Evaluated by Western Blot in A431 cell lysate. Western Blot Analysis: 1 µg/mL of this antibody detected Numb in 10 µg of A431 cell lysate. |
| Physical form【外形】 | Purified by Ion-Exchange Chromatography Format: Purified Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide. |
| Analysis Note【分析说明】 | Control A431 cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 6G10.1, monoclonal |
| species reactivity | human |
| technique(s) | immunocytochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgMκ |
| NCBI accession no.【NCBI登记号】 | NP_001005743 |
| UniProt accession no.【UniProt登记号】 | P49757 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... NUMB(8650) |
产品说明
| Target description【目标描述】 | ~70 kDa observed. Uniprot describes four isoforms at ~71 kDa (isoform 1), ~66 kDa (isoform 2), ~69 kDa (isoform 3), and ~65 kDa (isoform 4). |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
