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Anti-PDE4B2 Antibody
产品编号: | 4112005 |
规格: | from rabbit, purified by affinity chromatography |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-PDE4B2 Antibody
cAMP-specific 3′,5′-cyclic phosphodiesterase 4B, DPDE4, PDE32
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Phosphodiesterase 4B2 (PDE4B2) is a member of the PDE cyclic nucleotides. PDE4B2 is thought to contain both UCR1 and UCR2 regulatory units. PDE4B2 has been associated with schizophrenia and depression and could be a promising target for autism therapies. |
Specificity【特异性】 | This antibody recognizes PDE4B2 at the N-terminus. |
Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to the N-terminus of human PDE4B2. Epitope: N-terminus |
Application【应用】 | Research Sub Category GPCR, cAMP/cGMP & Calcium Signaling Research Category Signaling Anti-PDE4B2 Antibody is an antibody against PDE4B2 for use in WB. |
Quality【质量】 | Evaluated by Western Blot in Rat brain membrane tissue lysate. Western Blot Analysis: 1 µg/mL of this antibody detected PDE4B2 on 10 µg of Rat brain membrane tissue lysate. |
Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
Analysis Note【分析说明】 | Control Rat brain membrane tissue lysate |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
purified by【纯化方式】 | affinity chromatography |
species reactivity | rat |
species reactivity (predicted by homology) | human (immunogen homology) |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_001032416 |
UniProt accession no.【UniProt登记号】 | Q07343 |
shipped in【运输】 | wet ice |
Gene Information | human ... PDE4B(5142) |
产品说明
Target description【目标描述】 | ~78 kDa observed. UniProt describes 3 isoforms produced by alternative splicing: Isoform PDE4B1 at 83.3 kDa, Isoform PDE4B2 at 64.5 kDa, and Isoform PDE4B3 at 82.1 kDa |
Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |